Men with intermediate-risk prostate cancer may benefit from undergoing androgen-deprivation therapy (ADT) depending on how far the cancer has progressed, says a study published online Sept. 9, 2020, by JAMA Network Open. The results could help men better weigh risk versus reward when choosing their prostate cancer treatment options.
The study looked at men with intermediate-risk prostate cancer. This is the mid-range of prostate cancer in terms of aggressiveness between low-risk (which often doesn’t need treatment) and high-risk cancer. There are two categories of intermediate-risk cancer: favorable intermediate-risk (FIR) and the more advanced unfavorable intermediate-risk (UIR).
In the study, about 1,000 men with either UIR or FIR underwent radiation. Half also received four months of ADT — a hormone therapy that reduces androgens, such as testosterone, in the body and stops them from fueling prostate cancer cells. But it also can cause side effects, such as hot flashes, fatigue, mood swings, low sex drive, erectile dysfunction, loss of muscle mass, and weight gain.
After 15 years, those with FIR who had taken ADT lived, on average, about as long as those who did not have ADT. However, the UIR men who’d had ADT lived about eight months longer than the non-ADT group. Adding ADT also reduced the risk of cancer spreading in UIR men, but not in FIR men.
Bible verses for today’s meditation and inspiration: Matthew E. McLaren
And so we know and rely on the love God has for us. God is love. Whoever lives in love lives in God, and God in them. 1 John 4:16 NIV
Be completely humble and gentle; be patient, bearing with one another in love. Ephesians 4:2 NIV
We love because He first loved us. 1 John 4:19 NIV
Above all, love each other deeply, because love covers over a multitude of sins. 1 Peter 4:8 NIV
I pray that out of his glorious riches he may strengthen you with power through his Spirit in your inner being, so that Christ may dwell in your hearts through faith. And I pray that you, being rooted and established in love. Ephesians 3:16-17 NIV
And now these three remain: faith, hope and love. But the greatest of these is love. 1 Corinthians 13:13 NIV
Love must be sincere. Hate what is evil; cling to what is good. Romans 12:9 NIV
If I have the gift of prophecy and can fathom all mysteries and all knowledge, and if I have a faith that can move mountains, but do not have love, I am nothing. 1 Corinthians 13:2 NIV
Recommended contacts for prayer request and Bible study