Inflammatory bowel disease: Issues outside the gut

Inflammatory bowel disease (IBD) is a type of chronic inflammation of the gastrointestinal tract. Ulcerative colitis, marked by continuous inflammation of the large intestine, and Crohn’s disease, which causes patches of inflammation and can occur anywhere in the gastrointestinal tract, are both types of IBD. Patients with IBD can experience a variety of gastrointestinal symptoms such as abdominal pain, diarrhea, blood in their stool, bloating, and weight loss.

What conditions can occur outside the GI tract in people with IBD?

IBD symptoms can occur both inside and outside the gastrointestinal tract. The latter is known as extraintestinal manifestations (EIMs) of IBD. These conditions occur in nearly half of all people with IBD, and can be present before and/or after someone’s IBD is diagnosed. EIMs are more frequent in people who receive their diagnosis at an earlier age, and generally also occur earlier in the course of IBD. In fact, approximately 24% of EIM symptoms are present prior to receiving a diagnosis of IBD. The causes of EIMs are poorly understood but, similar to IBD, may be due to a combination of genetic risk factors, immune reactions, and lifestyle factors such as cigarette smoking.

What are some examples of extraintestinal manifestations of IBD?

Patients may have multiple EIMs at the same time, with varying severity. EIMs may not be easy to detect, and almost any organ system can be affected. Sometimes the severity of EIM symptoms mirrors that of the gut symptoms, but in certain conditions, the EIMs behave independently. Below are some common examples of extraintestinal manifestations.

Inflammatory bowel disease (IBD) is a type of chronic inflammation of the gastrointestinal tract. Ulcerative colitis, marked by continuous inflammation of the large intestine, and Crohn’s disease, which causes patches of inflammation and can occur anywhere in the gastrointestinal tract, are both types of IBD. Patients with IBD can experience a variety of gastrointestinal symptoms such as abdominal pain, diarrhea, blood in their stool, bloating, and weight loss.

What conditions can occur outside the GI tract in people with IBD?

IBD symptoms can occur both inside and outside the gastrointestinal tract. The latter is known as extraintestinal manifestations (EIMs) of IBD. These conditions occur in nearly half of all people with IBD, and can be present before and/or after someone’s IBD is diagnosed. EIMs are more frequent in people who receive their diagnosis at an earlier age, and generally also occur earlier in the course of IBD. In fact, approximately 24% of EIM symptoms are present prior to receiving a diagnosis of IBD. The causes of EIMs are poorly understood but, similar to IBD, may be due to a combination of genetic risk factors, immune reactions, and lifestyle factors such as cigarette smoking.

What are some examples of extraintestinal manifestations of IBD?

Patients may have multiple EIMs at the same time, with varying severity. EIMs may not be easy to detect, and almost any organ system can be affected. Sometimes the severity of EIM symptoms mirrors that of the gut symptoms, but in certain conditions, the EIMs behave independently. Below are some common examples of extraintestinal manifestations.

Whether or not you have been diagnosed with IBD, it is important to see your primary care doctor or gastroenterologist (if you have one) discuss any symptoms you may be experiencing. Your doctor(s) will discuss your medical and family history to determine your risk for IBD or other medical conditions.

For patients with a diagnosis of IBD or at risk for IBD, EIMs may be the first clue toward diagnosis or the need for treatment review and adjustment. It is important to communicate both your gastrointestinal and non-gastrointestinal symptoms with your gastroenterologist in order to promptly be started on the appropriate treatment and connected to specialists for the affected organ system. Lifestyle modifications such as smoking cessation may also reduce the risk of EIMs.

With targeted treatment and the appropriate healthcare team in place, management of both IBD and EIMs can be achieved to improve patients’ quality of life.

Bible verses for today’s meditation and inspiration: Matthew E. McLaren

2 Corinthians 13:9 For we rejoice when we ourselves are weak but you are strong; this we also pray for, that you be made complete.

Colossians 1:28 We proclaim Him, admonishing every man and teaching every man with all wisdom, so that we may present every man complete in Christ.

Colossians 4:12 Epaphras, who is one of your number, a bondslave of Jesus Christ, sends you his greetings, always laboring earnestly for you in his prayers, that you may stand perfect and fully assured in all the will of God.

2 Corinthians 10:15-16 not boasting beyond our measure, that is, in other men’s labors, but with the hope that as your faith grows, we will be, within our sphere, enlarged even more by you, so as to preach the gospel even to the regions beyond you, and not to boast in what has been accomplished in the sphere of another.

2 Thessalonians 1:3 We ought always to give thanks to God for you, brethren, as is only fitting, because your faith is greatly enlarged, and the love of each one of you toward one another grows ever greater;

2 Peter 3:18 but grow in the grace and knowledge of our Lord and Savior Jesus Christ To Him be the glory, both now and to the day of eternity. Amen.

Ephesians 1:17-18 that the God of our Lord Jesus Christ, the Father of glory, may give you a spirit of wisdom and revelation in the knowledge of Him. I pray that the eyes of your heart may be enlightened so that you will know what the hope of His calling is, what are the riches of the glory of His inheritance in the saints,

Ephesians 3:16-19 that He would grant you, according to the riches of His glory, to be strengthened with power through His Spirit in the inner man, so that Christ may dwell in your hearts through faith; and that you, being rooted and grounded in love, may be able to comprehend with all the saints what is the breadth and length and height and depth, read more

Recommended contacts for prayer requests and Bible study

www.agapetemplesda.com

www.adventistontario.org

https://www.hopechannel.com/au/learn/courses

breathoflife.tv/

https://3abn.org/all-streams/3abn.html

http://www.nadadventist.org/article/15/contact-us

https://www.adventist.org/en/utility/contact/

It Is Written

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