Switching from a “Western” diet with lots of fat and meat to a fiber-rich diet for just two weeks makes conditions in the large intestine less favorable to the development of colon cancer. The opposite switch may promote the formation of cancer.
That’s the conclusion from a small but elegant study done in urban Pittsburgh and rural KwaZulu-Natal, South Africa. It adds to a growing body of research that diet plays a large role in the development of colon cancer. The study also points a finger at bacteria living in the intestines, known as the gut microbiome, as a key link between diet and colon cancer.
An international team of researchers recruited 20 African American men and women living in Pittsburgh and 20 Africans living in KwaZulu-Natal. All of the volunteers had their diets scrutinized and their gut microbiomes analyzed. They also underwent colonoscopy. This inspection of the large intestine (the colon) showed that nine of the 20 Americans had polyps, small growths in the lining of the colon that can develop into cancer. No polyps were found in any of the 20 South Africans.
For two weeks, the Americans ate a traditional South African diet rich in fruits, vegetables, beans, and plant foods. The Africans ate a Western diet that had two to three times more fat and protein, including meat, than their traditional diet. Afterward, the participants again had colonoscopies and their gut microbiomes analyzed.
In just two weeks, significant changes occurred in the lining of the colon and in its chemical and bacterial make-up. Those following the African diet showed significant reductions in colon inflammation and other chemical signals that have been linked to colon cancer risk. In addition, their gut microbiomes generated more butyrate, a byproduct of fiber metabolism that can help prevent cancer. In contrast, those following the Western diet showed an increase in inflammation, a decrease in butyrate generation, and other changes that could lead to colon cancer.
Diet changes are quickly reflected in the colon
The idea that diet can influence colon cancer risk isn’t new. What’s surprising in this study is how quickly a change in diet altered conditions in the colon.
Colon cancer is the fourth leading cause of death from cancer around the world. It claims more than 600,000 lives each year. It is more common in some areas and less common in others. These differences reflect the influence of race, ethnicity, diet, physical activity, and other factors on the development of colon cancer.
In rural Africa, 5 out of 100,000 blacks develop colon. In the United States, 65 out of every 100,000 blacks develop the disease. That 13-fold increase isn’t likely to be explained by genetic differences.
You don’t need to follow a traditional African diet to help prevent colon cancer. Here are some dietary changes that can help:
- Eat a diet rich in fruits and vegetables.
- Choose whole grains, and foods made from them, instead of highly refined grains.
- Eat more beans and less red and processed meat.
- Get enough vitamin D through sunlight, diet, pills or all of these.
Having a colonoscopy every five years or so beginning at age 50 is another way to prevent colon cancer. It not only checks for the presence of cancer, but can remove potentially cancer-causing polyps.
Bible verses for today’s meditation and inspiration: Matthew E. McLaren
2 Corinthians 13:9 For we rejoice when we ourselves are weak but you are strong; this we also pray for, that you be made complete.
Colossians 1:28 We proclaim Him, admonishing every man and teaching every man with all wisdom, so that we may present every man complete in Christ.
Colossians 4:12 Epaphras, who is one of your number, a bondslave of Jesus Christ, sends you his greetings, always laboring earnestly for you in his prayers, that you may stand perfect and fully assured in all the will of God.
2 Corinthians 10:15-16 not boasting beyond our measure, that is, in other men’s labors, but with the hope that as your faith grows, we will be, within our sphere, enlarged even more by you, so as to preach the gospel even to the regions beyond you, and not to boast in what has been accomplished in the sphere of another.
2 Thessalonians 1:3 We ought always to give thanks to God for you, brethren, as is only fitting, because your faith is greatly enlarged, and the love of each one of you toward one another grows ever greater;
2 Peter 3:18 but grow in the grace and knowledge of our Lord and Savior Jesus Christ To Him be the glory, both now and to the day of eternity. Amen.
Ephesians 1:17-18 that the God of our Lord Jesus Christ, the Father of glory, may give to you a spirit of wisdom and of revelation in the knowledge of Him. I pray that the eyes of your heart may be enlightened so that you will know what is the hope of His calling, what are the riches of the glory of His inheritance in the saints,
Ephesians 3:16-19 that He would grant you, according to the riches of His glory, to be strengthened with power through His Spirit in the inner man, so that Christ may dwell in your hearts through faith; and that you, being rooted and grounded in love, may be able to comprehend with all the saints what is the breadth and length and height and depth, read more
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